evaluation of the anti–depressant activity of myristica fragrans (nutmeg) in male rats

نویسندگان

ghulam moinuddin department of pharmacology, al-ameen college of pharmacy, near lalbagh main gate, bangalore-560027. india

kshama devi department of pharmacology, al-ameen college of pharmacy, near lalbagh main gate, bangalore-560027. india

deepak kumar khajuria department of pharmacology, al-ameen college of pharmacy, near lalbagh main gate, bangalore-560027. india

چکیده

objective: the present study was undertaken to evaluate anti-depressant activity of myristica fragrans(ms). materials and methods: male wistar rats were subjected to imipramine and herbal extract ofms for their antidepressant activity using forced swimming test (fst), reserpine reversal test (rrt), haloperidol-induced catalepsy (hic), and pentobarbitone sleeping time (pst). results: administration of ms and imipramine revealed a statistically significant reduction in immobility time in fst, rrt, and protection against hic, compared to the control group. however, there was no significant potentiation of pst. conclusion: our study demonstrated the potential antidepressant activity of ms.

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منابع مشابه

Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats

Objective: The present study was undertaken to evaluate anti-depressant activity of Myristica fragrans(MS). Materials and Methods: Male Wistar rats were subjected to imipramine and herbal extract ofMS for their antidepressant activity using Forced Swimming Test (FST), Reserpine Reversal Test (RRT), Haloperidol-Induced Catalepsy (HIC), and Pentobarbitone Sleeping Time (PST). Results: Administr...

متن کامل

Evaluation of the anti–depressant activity of Myristica fragrans (Nutmeg) in male rats

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عنوان ژورنال:
avicenna journal of phytomedicine

جلد ۲، شماره ۲، صفحات ۷۲-۷۸

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